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Anti protease degradation Structural modification reduces its sensitivity to proteases, prolongs its half-life, and prolongs its duration of action

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Kawano J

Indeed, because more than 100 proteins have been reported as TG2 substrates and because TG2 has broad substrate specificity, the GST tag could be crosslinked with a number of cellular proteins 21

Mushrooms have refined these solutions over hundreds of millions of years, not to benefit humans, but to survive in the oxidatively hostile soil ecosystem